There is no consensus regarding the differences in Cerebrovascular Reactivity (CVR) magnitude differences between anterior and posterior circulations in healthy individuals. Forty-four healthy individuals underwent BOLD fMRI using a standardized blood vascular stress test achieved with sequential gas delivery. These results showed that cerebrovascular magnitude and speed of response tau) were stronger and faster in the posterior circulation compared to anterior circulation tissues. Therefore, the knowledge that there are significant regional differences in CVR is critical for investigating the regional impact of cerebrovascular pathologies.
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Levine et al. (2024) studied this question.
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