Localized 31P Magnetic Resonance Spectroscopy of Normal Human Kidneys at 3T

Phosphorous (31P) MR spectroscopy (MRS) can measure high energy phosphate metabolism non-invasively in vivo, which can provide metabolic insights into kidney pathophysiology. However, obtaining spectra from healthy volunteers for reference is challenging. In this study, we investigate the feasibility of localized 31P MRS in kidneys of healthy volunteers with a 3T clinical MR scanner. 31P spectra were successfully obtained in 10 healthy volunteers with metabolite ratio calculated to provide information about the energy metabolism.