What question did this study set out to answer?

To assess myocardial energy status using 31P-MRS at 7 T with improved precision for potential therapeutic monitoring.

February 22, 2026NMR in BiomedicineOpen Access

³¹ P‐MRS of the Human Heart at 7 T With an Integrated Whole‐Body ³¹ P Radiofrequency Transmit Coil

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To assess myocardial energy status using 31P-MRS at 7 T with improved precision for potential therapeutic monitoring.
Utilized integrated whole-body RF transmit coil for 31P spin excitation.
Conducted 31P-MRS on eight volunteers using a 20-mm isotropic resolution.
Employed a low-flip angle, short-repetition time 3D imaging sequence.
Quantified PCr, PDE, and Pi signals relative to ATP.
Performed Bland–Altman analyses to evaluate measurement repeatability.
Mid-septal myocardial PCr/ATP ratio was 1.85 ± 0.37.
Achieved a repeatability coefficient of 17.7% for PCr/ATP.
Found repeatability coefficients for Pi/ATP and PDE/ATP as 142.7% and 51.6%, respectively.
Demonstrated improved precision over previous lower magnetic field studies.

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Implication

Evaluates myocardial energy status in healthy volunteers using advanced 31P-MRS techniques, indicating improved measurement precision and noninvasive monitoring capabilities.

Cite This Study

Gosselink et al. (2026) studied this question.

synapsesocial.com/papers/699a9d27482488d673cd2ef2 https://doi.org/10.1002/nbm.70248

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Implication

Evaluates myocardial energy status in healthy volunteers using advanced 31P-MRS techniques, indicating improved measurement precision and noninvasive monitoring capabilities.

³¹ P‐MRS of the Human Heart at 7 T With an Integrated Whole‐Body ³¹ P Radiofrequency Transmit Coil

Key Points

Discussion

Implication

Cite This Study

³¹ P‐MRS of the Human Heart at 7 T With an Integrated Whole‐Body ³¹ P Radiofrequency Transmit Coil

Key Points

Discussion

Implication

Cite This Study

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