Whole brain T1 mapping has been performed using several different sequences but remains mostly confined to research applications. A clinically reliable and fast method to evaluate the white matter (WM) is important for accurate diagnosis, evaluating the severity of disease and monitoring disease progression over time. In this study we assessed Multiplied, Added, Subtracted and/or Divided Inversion Recovery (MASDIR) technique in nine healthy subjects and found evidence that such technique greatly improves the visualisation of tissue of interest and allows calculation of T1 values in a reliable, fast and clinically usable manner.
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Losa et al. (2024) studied this question.
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