4D-Flow and DCE-MRI Study on the Wall Enhancement of Unruptured Intracranial Aneurysms

This study used 4D-flow-MRI, dynamic contrast-enhanced MRI, and vessel wall MRI to explore the relationship between wall shear stress (WSS) and Ktrans and aneurysm wall enhancement (AWE) to understand the functional changes in the unruptured intracranial aneurysms (UIAs). Seventy-eight patients were enrolled, including 96 UIAs. All patients completed examinations based on a 3.0T Siemens Prisma magnetic resonance. WSS with the AWE group was lower, and Ktrans with the AWE group were higher than those without AWE. The wall enhancement index (WEI) was a quantitative index of AWE. WEI had a negative correlation with WSS and a positive correlation with Ktrans.