Application of Multiecho Dixon Technique and IVIM-DWI in Patients with Primary Osteoporosis : A Preliminary Study with 3.0 T MRI

Bone mineral density (BMD) is a common standard for evaluating osteoporosis, but it can only reflect the change of bone mass, not the microscopic nodules of tissueChange of structure. Multi-echo Dixon and IVIM-DWI were used to evaluate the changes of spinal bone marrow microstructure in osteoporosis, osteopenia and normal subjects. The results showed that there were significant differences in FF, D and D* between osteoporosis, osteopenia and normal subjects. These results indicate that IVIM-DWI can quantitatively reflect the changes of lumbar microcirculation and fat content, and can be used as a biomarker for the progression of osteoporosis.