Correlation of MRI Radiomics Features and Recurrence After Gamma Knife Treatment in Parasagittal and Falx Meningiomas

Meningiomas located at and around the falx and superior sagittal sinus are known to have a more aggressive clinical behavior. Additionally, their localization and invasion characteristics make complete resection difficult, creating a need for radiosurgery. This study assessed the relationship between radiomics/clinical features of parasagittal and falx meningiomas and their recurrence-free survival after Gamma Knife. The radiomics and clinical features (age, pre-op tumor volume, coverage, and sensitivity) were analyzed together. Univariable Cox analysis associated maximum and skewness of T1 lesion, age, TV, and coverage, whereas multivariable Cox analysis associated skewness of T2 lesion, coverage, and selectivity with RFS.