In this study we evaluated the diagnostic performance of whole-body T2-weighted imaging with uniform 2-point Dixon fat-suppression for the detection of multiple myeloma. Furthermore, we evaluated the added sensitivity, change in disease stage, and change in treatment plan with the sequential addition of DWI and FDG PET. T2-Dixon demonstrated higher sensitivity than both DWI and PET. Adding DWI did not change stage or treatment plan. However, the addition of PET did change the treatment plan in one patient with extra-osseous disease. Whole-body PET-MRI with T2-Dixon is a promising and efficient tool for assessment of multiple myeloma.
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Heijden et al. (2024) studied this question.
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