This study explores the predictive value of gadoxetic acid-enhanced magnetic resonance imaging (MRI) features on the pathologic grade, microvascular invasion (MVI), and cytokeratin-19 (CK19) expression in hepatocellular carcinomas (HCC), and evaluates their association with postoperative recurrence of HCC. The main method is to investigate whether there are independent predictors of the above aggressive indicators in the gadoxetic acid-enhanced MRI features and clinical parameters. Our study shows that peritumoral enhancement, peritumoral hypointensity and rim enhancement could independently predict poor pathological grade, MVI and CK19, respectively. Consequently, these results may help HCC patients develop more appropriate treatment options.
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Lu et al. (2024) studied this question.