Assessment of early anthracycline-induced cardiotoxicity using segmental strain of cardiac magnetic resonance : an animal study

This study investigated segmental strain to evaluate early anthracycline-induced cardiotoxicity on a 1.5T MR system in New Zealand rabbits models. The apical lateral wall and the anterior apical wall have a statistical difference corresponding to the pathological results in the second week. The ejection fraction showed statistical difference at the eighth week, while the global strain was not even statistically significant. The result showed that the peak segmental strain was earlier than the peak global strain and cardiac function, which may provide an effective and convenient monitoring method for chemotherapy patients.