Why the study?
Does two-dimensional myocardial strain imaging detect changes in left ventricular systolic function earlier than LVEF immediately after anthracycline chemotherapy in women with breast cancer?
Population
52 women with histologically confirmed breast cancer
Comparison
Anthracycline chemotherapy vs Baseline (1 week before chemotherapy)
Design
Cohort
Follow-up
1 week after chemotherapy
Authors
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May identify subclinical LV impairment post-anthracycline before LVEF change; hypothesis-generating for strain-guided monitoring in breast cancer.
Does two-dimensional myocardial strain imaging detect changes in left ventricular systolic function earlier than LVEF immediately after anthracycline chemotherapy in women with breast cancer?
Two-dimensional myocardial strain imaging detects early impairment of myocardial function immediately after anthracycline treatment before detectable changes in LVEF.
Stoodley et al. (2011) studied this question.
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