Why the study?
Does anthracycline chemotherapy alter left ventricular diastolic function in women with breast cancer?
Population
52 women with histologically confirmed breast cancer
Comparison
Anthracycline chemotherapy vs Baseline (pre-chemotherapy)
Design
Cohort
Follow-up
1 week following chemotherapy
Authors
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May support post-anthracycline diastolic monitoring in breast cancer; extends speckle tracking utility but remains hypothesis-generating.
Does anthracycline chemotherapy alter left ventricular diastolic function in women with breast cancer?
Early alterations in LV diastolic function occur immediately after anthracycline chemotherapy and correlate with reduced systolic function, detectable by 2D speckle tracking echocardiography.
Stoodley et al. (2012) studied this question.
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