This study investigated and compared the feasibility of whole tumor based texture analysis of various magnetic resonance diffusion imaging as early predictors of the clinical response to chemotherapy in patients with colorectal liver metastases (CRLM). The results showed that baseline DWI parameters and the follow-up changes of IVIM and DKI parameters can be conductive to predict the chemotherapeutic response of patients with CRLM. And Changes in D-parameters (Δ% DMean, Δ% D5th percentile, and Δ% DDiff-entropy) are superior to other diffusion related parameters. This suggests that DKI-related parameters could effectively predict the response in short period after treatment (2-3 weeks).
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Li et al. (2024) studied this question.
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