Evaluation of pulmonary artery hemodynamic changes in COPD patients with different emphysema volume by using 4D-Flow MRI

Few studies quantitatively evaluate pulmonary artery hemodynamic changes caused by emphysema. 34 COPD patients were divided into two groups according to emphysema volume and 12 healthy volunteers were matched. Hemodynamic parameters were calculated by 4D-Flow MRI and right ventricular function indicators were evaluated for three groups. The right systolic pressure drop and RVEF were lower in moderate and severe emphysema group but the right EL was higher. The whole-lung emphysema score correlated negatively with RVEF and the right systolic pressure drop. 4D-Flow combined with cine image can comprehensively evaluate the pulmonary artery hemodynamics and right ventricular function of COPD patients.