Why the study?
Is right-ventricular contractility preserved in COPD patients with pulmonary hypertension despite reduced RVEF?
Population
24 patients with chronic obstructive pulmonary disease (COPD)
Comparison
Combined hemodynamic and radionuclide assessment… vs COPD patients without pulmonary hypertension
Design
Cross-sectional
Authors
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May indicate afterload dependence of RVEF rather than contractility loss in COPD-PH; leaves open prospective validation of load-independent RV assessment.
Is right-ventricular contractility preserved in COPD patients with pulmonary hypertension despite reduced RVEF?
In stable COPD patients, right-ventricular contractility is well preserved even in the presence of pulmonary hypertension, and RVEF is highly afterload-dependent, making it a poor indicator of overall right-ventricular function.
Burghuber et al. (2009) studied this question.
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