What question did this study set out to answer?

September 16, 2013Egyptian Journal of Chest Diseases and TuberculosisOpen Access

Evaluation of left ventricular function in patients with chronic obstructive pulmonary disease with or without pulmonary hypertension

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Why the study?

Is left ventricular function impaired in patients with COPD with or without pulmonary hypertension compared to healthy controls?

Population

36 patients with chronic obstructive pulmonary disease without additional cardiac diseases and 12 age and…

Design

Case-control

Authors

RWRabab A. El WahshMenoufia University MAMahmoud AhmedNational Authority for Remote Sensing and Space Sciences RYRehab YaseenMenoufia University

Discussion

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Implication

LV dysfunction may link to COPD with PH; leaves open whether screening improves outcomes.

Key Points

To evaluate left ventricular systolic, diastolic, and global function in patients with chronic obstructive pulmonary disease with and without pulmonary hypertension.
Assessed 36 patients with chronic obstructive pulmonary disease without additional cardiac diseases and 12 age- and sex-matched healthy controls.
Performed spirometry along with standard and tissue Doppler echocardiography to measure myocardial velocities, filling pressures, and performance index.
Left ventricular systolic function showed no significant difference between groups, but left ventricular diastolic and global function were significantly impaired across advancing disease stages.
Patients with pulmonary hypertension (55.6% of the cohort) demonstrated significantly lower tissue Doppler E wave peak velocity (P ≤ 0.05), reduced tissue Doppler E/A ratio (P ≤ 0.01), and a higher myocardial performance index (P ≤ 0.05) compared to patients with normal pulmonary pressure.

Structured PICO

Is left ventricular function impaired in patients with COPD with or without pulmonary hypertension compared to healthy controls?

Population

36 patients with chronic obstructive pulmonary disease (COPD) without additional cardiac diseases (20 with pulmonary hypertension) and 12 age and sex-matched healthy subjects.

Comparator

12 age and sex-matched healthy subjects; internal comparison of COPD patients with versus without pulmonary hypertension.

Outcome

Left ventricular systolic, diastolic, and global function assessed by standard and tissue Doppler echocardiography.surrogate

COPD patients, particularly those with pulmonary hypertension or advanced disease, exhibit significant left ventricular diastolic and global dysfunction detectable by tissue Doppler echocardiography.

Cite This Study

Wahsh et al. (2013) studied this question.

synapsesocial.com/papers/6a7cc411469490254d190b2e https://doi.org/10.1016/j.ejcdt.2013.08.004

View Full Paper

Ask AI

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Evaluation of left ventricular function in patients with chronic obstructive pulmonary disease with or without pulmonary hypertension

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Evaluation of left ventricular function in patients with chronic obstructive pulmonary disease with or without pulmonary hypertension

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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