Key result
In stable COPD patients without apparent LV disease, LV diastolic dysfunction was present in 84% and significantly associated with age, illness duration, GOLD stage, and ECG/CXR findings (P<0.001).
Why the study?
Patients with COPD may have left ventricular dysfunction, even in the absence of known LV diseases.
Population
300 stable COPD patients without apparent LV disease and 100 age- and sex-matched healthy subjects
Comparison
Stable COPD patients vs age- and sex-matched healthy controls
Design
Cross-sectional observational analytical study
Authors
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May warrant cardiac evaluation in stable COPD; leaves open prognostic value and management implications pending prospective data.
Cross-Sectional (n=400)
p-value: p=<0.001
Stable COPD patients without apparent clinical heart disease have a high prevalence of echocardiographic LV diastolic dysfunction that correlates with COPD severity.
Saha et al. (2023) conducted a cross-sectional in Chronic obstructive pulmonary disease (COPD) (n=400). Chronic obstructive pulmonary disease (COPD) vs. Age- and sex-matched healthy subjects was evaluated on LV diastolic dysfunction (p=<0.001). In stable COPD patients without apparent LV disease, LV diastolic dysfunction was present in 84% and significantly associated with age, illness duration, GOLD stage, and ECG/CXR findings (P<0.001).
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