Key result
Subclinical left ventricular systolic dysfunction was highly prevalent in COPD patients, with abnormal myocardial performance index in 64.9% of those without and 88.5% with pulmonary hypertension.
Why the study?
The authors sought to assess the prevalence of left ventricular systolic and diastolic dysfunction in stable COPD patients without pre-existing left ventricular disease.
Population
100 COPD outpatients in GOLD II-IV and 34 controls
Comparison
COPD with PH vs COPD without PH vs controls
Design
Observational cohort study
Authors
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May support echocardiography screening in COPD; hypothesis-generating and should not yet change practice.
Cross-Sectional (n=134)
No
p-value: p=<0.01
Subclinical left ventricular systolic dysfunction is highly prevalent in patients with COPD, even in those with normal pulmonary artery pressure and no overt cardiovascular disease.
Hilde et al. (2020) conducted a cross-sectional in Chronic obstructive pulmonary disease (COPD) (n=134). Chronic obstructive pulmonary disease (COPD) vs. Healthy controls was evaluated on Prevalence of abnormal left ventricular myocardial performance index (LV MPI ≥0.51) and LV strain (≥-15.8%) (p=<0.01). Subclinical left ventricular systolic dysfunction was highly prevalent in COPD patients, with abnormal myocardial performance index in 64.9% of those without and 88.5% with pulmonary hypertension.
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