Key result
COPD patients with pulmonary hypertension had significantly impaired global ventricular function compared to healthy controls, demonstrated by a higher right ventricular myocardial performance index (0.96 vs 0.42, p<0.001).
Why the study?
Does COPD, with or without pulmonary hypertension, impair left and right ventricular global function as measured by myocardial performance index compared to healthy controls?
Population
90 subjects, including 60 patients with chronic obstructive pulmonary disease without additional cardiac…
Design
Cross-sectional
Authors
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RV dysfunction in COPD-PH may warrant closer cardiac monitoring; leaves open prognostic value and prospective validation of MPI.
Cross-Sectional (n=90)
No
Does COPD, with or without pulmonary hypertension, impair left and right ventricular global function as measured by myocardial performance index compared to healthy controls?
Absolute Event Rate: 0.96% vs 0.42%
p-value: p=<0.001
Tissue Doppler-derived myocardial performance index reveals that both left and right ventricular global and diastolic functions are impaired in COPD patients, particularly those with concurrent pulmonary hypertension.
Prof.Dr. Basil Najeebsaeed (2016) conducted a cross-sectional in Chronic Obstructive Pulmonary Disease (n=90). Chronic Obstructive Pulmonary Disease with Pulmonary Hypertension vs. Healthy controls was evaluated on Right Ventricular Myocardial Performance Index (RVMPI) (p=<0.001). COPD patients with pulmonary hypertension had significantly impaired global ventricular function compared to healthy controls, demonstrated by a higher right ventricular myocardial performance index (0.96 vs 0.42, p<0.001).
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