Key result
A history of chronic obstructive pulmonary disease was not associated with a significantly decreased right ventricular ejection fraction compared to controls (46.8 vs 50.8, p=0.29).
Observational (n=157)
This study suggests that right ventricular ejection fraction is not significantly decreased in patients with COPD compared to controls.
Background: Prevalence of right ventricular dysfunction in patients with chronic obstructive lung disease (COPD) is controversial. The goal of this study was to evaluate the prevalence of decreased right ventricular ejection fraction RVEF in patients with the diagnosis of COPD in comparison to a control group. Methods: A series of 157 patients, who underwent LVEF assessment using blood pooled scintigraphy for clinical indications, underwent simultaneous measurement of RVEF. Patients with a history of COPD were compared to a control group. Results: LVEF was measured in 155 and RVEF was measured in 152 patients. Mean LVEF in patient with COPD (13 patients) was 46.5 ± 16.8 SD vs. 53.2 ± 16.4 SD in the control group (142 patient) p=0.16. Mean RVEF in patient with COPD (12 patients) was 46.8± 13.9 SD vs. 50.8 ± 12.7 SD in the control group (140 patients), p=0.29. Subgroups analysis of mild, moderate or severely decreased LVEF and RVEF revealed no statistical differences between the patients with or without the diagnosis of COPD. Conclusion: RVEF appears to be similar in patients with or without COPD.
No takes yet. Share an insight, caveat, or question.
A 2008 study conducted an observational in Chronic obstructive pulmonary disease (n=157). History of chronic obstructive pulmonary disease vs. No history of chronic obstructive pulmonary disease was evaluated on Right ventricular ejection fraction (RVEF) (p=0.29). A history of chronic obstructive pulmonary disease was not associated with a significantly decreased right ventricular ejection fraction compared to controls (46.8 vs 50.8, p=0.29).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: