Therapeutic strategies and clinical evolution in pediatric fibrosarcoma: a case report

Congenital infantile fibrosarcoma (IFS) is rare and represents less than 1% of all childhood cancers. It is a tumor that originates in the connective fibrous tissue found at the ends of long bones and then spreads to other surrounding soft tissues. These lesions are typically large, grow rapidly, and diagnosis is confirmed by histopathology, where cellular proliferation of fibroblasts occurs. The surgical resection is the primary treatment; however chemotherapeutic agents may be used as adjuvant therapy. We herein report IFS in the arm of child patient, who had a large localized tumoral mass with a rapid evolution and non-responsible to usual chemotherapy, despite being characterized by low rates of relapse and better median survival.