Objectives The purpose of this study is to confirm the factors affecting the patient safety management knowledge, attitude, and confidence in performance on standard precaution performance in nursing students. Methods A questionnaire survey was conducted on 204 nursing college students attending 2 university. The data of this study were analyzed by means of SPSS WIN 20.0 program, mean and standard deviation, pearson's correlation coefficients and stepwise multiple regression analysis. Results Results of this study, patient safety management attitudes of nursing students were positively correlated with patient safety management performance confidence(r=.356, p<.001) and safety management knowledge(r=-.176, p=.019), attitude(r=.253, p<.001), and patient safety management performance confidence was positively correlated with standard attention performance(r=.453, p<.001). The predictive factor affecting the standard precaution performance of nursing students was patient safety management performance confidence(β=.407, p<.001), and the explanatory power of the standard precaution performance was 22.8%. Conclusions Patient safety management performance confidence is an important variable, because it is to improve the standard precaution performance of nursing students. It is suggested to develop a nursing education program to improve patient safety management performance confidence.
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