In vitro, ex vivo, instrumental and clinical evaluation of a topical cream on the signs of periorbital ageing
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Discussion
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Implication
Clinical and laboratory evaluation demonstrates significant reduction of periorbital ageing signs in 33 women, highlighting multi-target tissue remodeling.
Key Points
- Topical eye cream application visibly reduces periorbital ageing signs, restoring skin firmness while diminishing both wrinkle appearance and dark circles.
- Skin hydration improved within 15 min, whereas instrumental wrinkle depth decreased within 7 days alongside reduced transepidermal water loss.
- In vitro, ex vivo, and clinical analyses confirm elevated collagen iv and filaggrin expression, indicating coordinated cellular and barrier rejuvenation.
Cite This Study
D’Arcangelis et al. (2024) studied this question.