An Investigation Into the D- Dimer Levels in Srinagar, Jammu and Kashmir, Covid -19 Patients

Objectives:The COVID-19 pandemic is one of the major global health emergencies of the 21 st century.D-dimer as a biomarker for COVID-19-associated Coagulopathy elevated D-dimer levels among Covid-19 patients suggest a heightened state of Coagulation Activation and Fibrinolysis, potentially indicative of increased thrombotic risk and disease severity.Thus, investigating the connection between D-Dimer levels and COVID-19 patient severity is the aim of the current study. Methodology:The present study employed a retrospective cross-sectional design to investigate D-dimer levels in 80 COVID-19 patients in the Department of Hematology at a designated healthcare facility of Srinagar, Jammu and Kashmir, India.Measurement of D-dimer concentration in the serum retrospectively retrieved from laboratory reports in the medical records. Results:The results showed that the mean D-dimer level of the COVID-19 patients was 250.35±57.8ng/mL.Of those 80 subjects (40male and 40 female).The Pearson correlation coefficient (r=0.42)showed highly significant positive correlation (p<0.05) between the D-dimer level and COVID-19 severity. Conclusion:The D-dimer levels were notably higher in COVID-19 patients, suggesting a heightened risk of coagulopathy and thrombotic events in these individuals.The findings underscored the diagnostic utility of Ddimer's potential as a diagnostic marker for thrombotic complications and coagulopathy in COVID-19 patients.