⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

August 7, 2024MoleculesOpen Access

A New Class of Benzo[b]thiophene-chalcones as Cholinesterase Inhibitors: Synthesis, Biological Evaluation, Molecular Docking and ADME Studies

Giovanna Delogu Michela Begala María João Matos Davide Crucitti Valeria Sogos Benedetta Era Antonella Fais

View Full Paper

Ask AI

Bookmark

Share

Abstract

In this study, heterocyclic compounds containing a benzothiophene scaffold were designed and synthetized, and their inhibitory activity against cholinesterases (ChE) and the viability of SH-SY5Y cells have been evaluated. Benzothiophenes

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Delogu et al. (2024) studied this question.

synapsesocial.com/papers/68e5d246b6db6435875685be https://doi.org/10.3390/molecules29163748

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Design, Synthesis, and Cholinesterase Inhibitory Evaluation of Novel 5-(Benzylthio)-1,3,4-thiadiazole DerivativesOriginal Research · 2026
2Design, Synthesis and Cholinesterase Inhibitory Activity of Novel 1,3,4-Thiadiazole Derivatives2024 · 3 citations
3Organo Mediated Sustainable Synthesis and In‐Silico Studies of Novel Benzisoxazole‐Chromene Acyl Hydrazones as AChE Inhibitors2024 · 5 citations
4Exploring Novel Schiff Base Compounds Derived from Benzothiophene-3- carboxaldehyde Hydrazones: In vitro and In silico Evaluation as Potential Inhibitors of Cholinesterases and Carbonic Anhydrases I-II2024 · 1 citations
5Computational drug design, synthesis, acetylcholinesterase inhibition and kinetic evaluation of novel benzothiazole-thiadiazole/oxadiazole derivativesOriginal Research · 2026

More related papers

Benzimidazole derived hydrazone Schiff bases as potent cholinesterase inhibitors: synthesis, <i>in vitro</i> and <i>in silico</i> approaches2026
Design, Synthesis, and X-ray Characterization of Benzohydrazide Derivatives as Cholinesterase Inhibitors for the Treatment of Alzheimer’s Disease: An Experimental and Computational Approach to Biological Activity2026
Photochemically Assisted Synthesis of Thienobenzotriazole-Based Dual Cholinesterase Inhibitors2025

More from Molecules

Micropropagation of the Endemic Stachys pinardii Boiss. and Comparative Investigation of the Phytochemical Composition of Cultured and Wild-Grown PlantsWed,
Wool–Poly(lactic acid) Biocomposite Mats as Degradable Sulphur Carriers: Effects on Forage Elemental Composition and Material DegradationWed,