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August 7, 2024EpigeneticsOpen Access

GGNBP2 regulates histone ubiquitination and methylation in spermatogenesis

Kaimin Guo Yin Cao Zhiyi Zhao Jiantao Zhao Lingyun Liu Hongliang Wang

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Abstract

Gametogenetin binding protein 2 (GGNBP2) was indispensable in normal spermatids for transformation into mature spermatozoa in mice, and when Gametogenetin binding protein 2 is bound to BRCC36 and RAD51, the complex participates in repairing DNA double-strand breaks (DSB) during the meiotic progression of spermatocytes. Ggnbp2 knockout resulted in the up-regulation of H2A

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Cite This Study

Guo et al. (2024) studied this question.

synapsesocial.com/papers/68e5d24cb6db643587568628 https://doi.org/10.1080/15592294.2024.2381849

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