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August 7, 2024Current Eye Research

ASPP2 Upregulation as a Novel Approach to TGF-β2-Induced Proliferative Vitreoretinopathy In Vivo and In Vitro

Xiaoli Chen Yankun Yue Haiwei Wang Lu Liu

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Abstract

Purpose Proliferative vitreoretinopathy (PVR) can cause blindness and the pathogenesis is unclear. Transforming growth factor (TGF)-β-induced epithelial-mesenchymal transition (EMT) of RPE cells is vital. P53 protein 2 (ASPP2) was previously reported to inhibit EMT in PVR rats, but the specific mechanism is unveiled.

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Cite This Study

Chen et al. (2024) studied this question.

synapsesocial.com/papers/68e5d34fb6db64358756976b https://doi.org/10.1080/02713683.2024.2388686

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