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August 6, 2024International Journal of Molecular SciencesOpen Access

Heterogeneous IL-9 Production by Circulating Skin-Tropic and Extracutaneous Memory T Cells in Atopic Dermatitis Patients

Irene García‐Jiménez Lídia Sans‐de San Nicolàs Laia Curto‐Barredo Marta Bertolín‐Colilla Eloi Sensada-López Ignasi Figueras‐Nart Montserrat Bonfill‐Ortí Antonio Guilabert-Vidal Anna Ryzhkova Marta Ferrán Giovanni Damiani Tali Czarnowicki Ramón M. Pujol Luis F. Santamaria‐Babí

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Abstract

Interleukin (IL)-9 is present in atopic dermatitis (AD) lesions and is considered to be mainly produced by skin-homing T cells expressing the cutaneous lymphocyte-associated antigen (CLA). However, its induction by AD-associated triggers remains unexplored. Circulating skin-tropic CLA

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García‐Jiménez et al. (2024) studied this question.

synapsesocial.com/papers/68e5d358b6db643587569d88 https://doi.org/10.3390/ijms25168569

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Memory Cells in Atopic Dermatitis: Paving the Way to Disease ModificationOriginal Research · 2026 · 2 citations
2A shift towards a type I immune response in chronic atopic dermatitis favours an IL-15 dependent tissue resident memory cell nicheOriginal Research · 2026
3Increased frequency of intracellular interleukin (IL)-13 and IL-10, but not IL-4, expressing CD4+ and CD8+ peripheral T cells of patients with atopic dermatitisOriginal Research · 2002 · 57 citations
4Mast cells are one major source of interleukin-4 in atopic dermatitisOriginal Research · 1994 · 150 citations
5IL-9 Production by Peripheral Blood Mononuclear Cells of Atopic AsthmaticsOriginal Research · 2007 · 11 citations

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