HKUST‐1 Derived Cu₂S‐Cu₃P@C Nanomatrix Electrode Material for Non‐Enzymatic Electrochemical Glucose Sensing

Robust Cu 2 S‐Cu 3 P@C Nanomatrix electrode material has been synthesized via a two‐step process involving carbonization of Cu‐MOF, HKUST‐1, followed by simultaneous phosphorization and sulphurization of the carbonized product. This seamless approach leads to the efficient incorporation of highly active Cu 2 S‐Cu 3 P hybrid nanostructures within a conductive carbon matrix, exhibiting exceptional electrochemical glucose sensing performance. Synergistic interactions between Cu 2 S‐Cu 3 P and the carbon matrix boost glucose electro‐oxidation kinetics. The resulting Cu 2 S‐Cu 3 P@C displays a broad linear response (0.005–5 mM), low detection limit (2.3 μM), and high sensitivity (10,790 μA mM −1 cm −2 ), with excellent selectivity towards glucose even in the presence of interferents. This biomimetic Cu 2 S‐Cu 3 P@C nanomatrix catalyst holds promise for biosensor development in bioanalysis and clinical diagnosis.