Clinical review demonstrates altered voltage-gated sodium channel activity in patients with ciguatera poisoning, highlighting critical considerations for anesthesia management.
Ciguatoxin, a potent neurotoxin from tropical and subtropical fish, causes ciguatera fish poisoning, presenting with a spectrum of gastrointestinal, neurological, and cardiovascular symptoms. Ciguatoxin affects the voltage-gated sodium channels in the body, so there is a need for additional considerations for administering anesthesia in patients with ciguatera poisoning. Understanding the long-term implications of ciguatoxin exposure is essential for optimizing anesthesia management in these patients.
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Mohta et al. (2024) studied this question.
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