Microtube self-assembly leads to conformational freezing point depression

Multi-walled tubular aggregates formed by hierarchical self-assembly of beta-cyclodextrin (β-CD) and sodium dodecylsulfate (SDS) hold a great potential as microcarriers. However, the underlying mechanism for this self-assembly is not well understood. To advance the application of these structures, it is essential to fine-tune the cavity size and comprehensively elucidate the energetic balance driving their formation: the bending modulus versus the microscopic line tension.