This study investigates the representativeness of the 'All of Us' Type 2 Diabetes (T2DB) cohort by comparing it with the demographic diversity of the Behavioral Risk Factor Surveillance System (BRFSS) benchmark. We identified 33,587 individuals within the AoU cohort using established computational phenotypes, noting significant disparities in race-age distributions. The analysis underscores the need for enhanced data collection strategies and targeted recruitment to reduce biases and improve research validity.
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Zheng et al. (2024) studied this question.
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