Analysis reveals unresolved colonic muscularis macrophage diversity in colitis, highlighting that muscularis propria inflammation worsens inflammatory bowel disease.
Immune cell populations in the intestinal muscularis propria during colitis are poorly resolved. Maintaining homeostasis in this niche is critical, highlighted by the poorer prognosis of inflammatory bowel disease associated with muscularis propria inflammation.
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Ohishi et al. (2024) studied this question.
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