⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

August 5, 2024Computers in Biology and MedicineOpen Access

A novel ionic model for matured and paced atrial-like human iPSC-CMs integrating IKur and I<mml:mrow…

Sofia Botti Chiara Bartolucci Claudia Altomare Michelangelo Paci Lucio Barile Rolf Krause Luca F. Pavarino Stefano Severi

View Full Paper

Ask AI

Bookmark

Share

Abstract

This work introduces the first atrial-specific in-silico human induced pluripotent stem cells-derived cardiomyocytes (hiPSC-CMs) model, based on a set of phenotype-specific I

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Botti et al. (2024) studied this question.

synapsesocial.com/papers/68e5d682b6db64358756bfd3 https://doi.org/10.1016/j.compbiomed.2024.108899

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1A novel ionic model for matured and paced atrial–like hiPSC–CMs integrating <i>I</i> <sub> <i>Kur</i> </sub> and <i>I</i> <sub> <i>KCa</i> </sub> currentspreclinical · 2024
2Structural Immaturity of Human iPSC-Derived Cardiomyocytes: In Silico Investigation of Effects on Function and Disease Modelingpreclinical · 2018 · 171 citations
3A novel computational model of human iPSC-derived ventricular myocytes with improved L-type calcium current for application to Timothy syndromepreclinical · 2026
4Computational Model for Simulating Drug-Induced Arrhythmia Sensitivity of Human iPSC-derived Cardiomyocytespreclinical · 2017
5In Silico Human Induced Pluripotent Stem Cell Derived Cardiomyocyte Electro-Mechanical Modelling and Simulationpreclinical · 2021