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August 5, 2024Clinical EpigeneticsOpen Access

Impact of childhood maltreatment on aging: a comprehensive Mendelian randomization analysis of multiple age-related biomarkers

Zheng Zhang Hao Ren Rong Han Qiyin Li Jiangyou Yu Yuan H. Zhao Liwei Tang Yadong Peng Ying Liu Cheng Gan Keyi Liu Qinghua Luo Haitang Qiu Chenggang Jiang

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Abstract

Childhood maltreatment (CM) is linked to long-term adverse health outcomes, including accelerated biological aging and cognitive decline. This study investigates the relationship between CM and various aging biomarkers: telomere length, facial aging, intrinsic epigenetic age acceleration (IEAA), GrimAge, HannumAge, PhenoAge, frailty index, and cognitive performance.

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Cite This Study

Zhang et al. (2024) studied this question.

synapsesocial.com/papers/68e5d682b6db64358756c05c https://doi.org/10.1186/s13148-024-01720-z

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