A protein database to study the origin of metazoans

and curated eukaryotic database.It consolidates information from EukProt (Richter et al. 2022) and various other resources to enhance Metazoa representation in existing protein databases.The preprint is of significant interest to the phylogenomics and comparative genomics communities, and I commend the author for their work.LukProt, the expanded database, significantly increases the taxon sampling within holozoans.It integrates data from the previously assembled EukProt and AniProtDB (Barreira et al. 2021) databases, with additional datasets from early-diverging animal lineages such as ctenophores, sponges, and cnidarians.This effort will undoubtedly be useful for researchers investigating these clades and their origins, as well as for the broader field of comparative genomics.The author provides both web-portal and command-line versions of the database, making it accessible to users with varying degrees of bioinformatic proficiency.The curation effort is commendable, and I believe the comparative genomics community, especially those interested in animal origins, will find LukProt to be a valuable resource.