A 29-year-old man with Ewing sarcoma in the right ankle underwent 68 Ga-DOTA-IBA PET/CT and 18 F-FDG PET/CT, both of which showed high radiotracer activity for the primary tumor. Interestingly, bone metastases were detected early using 68 Ga-DOTA-IBA PET/CT for the sixth thoracic vertebrae and with 18 F-FDG PET/CT for the bilateral humerus. Higher uptake of 68 Ga-DOTA-IBA was found in both primary and metastatic sites of Ewing sarcoma. 177 Lu-DOTA-IBA may be one of the possible therapies for metastatic or recurrent Ewing sarcoma.
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Xiang et al. (2024) studied this question.
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