REPORTmetastases are more frequently observed in males compared to females (1.73:1). 3 IntroductIonOral metastatic tumors are uncommon, making for just around 1% of all oral malignant neoplasms. 1These metastatic tumors have significant clinical implications since they could be the first indication of cancer going unnoticed at a distant original site. 2 Oral metastases are found in roughly 20% of instances before the distant source tumor is found. 1 According to published research, metastatic cancers in the oral region are most often caused by the breast, lung, kidney, thyroid gland, intestine, prostate gland, stomach, testis, and bladder. 2 Oral metastasis can affect either bone structures, soft tissues, or both.Bone structures are more commonly affected than soft tissues.In a small percentage of cases (5.4%), the metastasis spreads to multiple sites within the oral cavity.The mandible is the most commonly affected location, followed by the gingiva, maxilla, and tongue.When considering sex differences in metastasis to hard tissues, there is a similar distribution between males and females (1.2:1), with a slight male predominance.
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Garlapati et al. (2024) studied this question.
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