⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

August 4, 2024International Journal of Molecular SciencesOpen Access

IFN-β Overexpressing Adipose-Derived Mesenchymal Stem Cells Mitigate Alcohol-Induced Liver Damage and Gut Permeability

Soonjae Hwang Young Woo Eom Seong Hee Kang Soon Koo Baik Moon Young Kim

View Full Paper

Ask AI

Bookmark

Share

Abstract

Alcoholic liver disease (ALD) is a form of hepatic inflammation. ALD is mediated by gut leakiness. This study evaluates the anti-inflammatory effects of ASCs overexpressing interferon-beta (ASC-IFN-β) on binge alcohol-induced liver injury and intestinal permeability. In vitro, ASCs were transfected with a non-viral vector carrying the human

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Hwang et al. (2024) studied this question.

synapsesocial.com/papers/68e5d78ab6db64358756dd46 https://doi.org/10.3390/ijms25158509

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Glutamate excreted by LepR⁺ BM-MSCs mitigates alcohol-associated liver disease by promoting IL-1R2⁺ monocyte migrationOriginal Research · 2026
2Overexpression of microRNA-126 in Adipose-Derived Mesenchymal Stem Cells Alleviate the Alcoholic Liver Injury2024
3Inflammation and gut microbiota in the alcoholic liver disease2024 · 50 citations
4Blocking the gut–liver IgA axis attenuates macrophage-mediated inflammation and injury in alcohol-associated liver diseaseCross-Sectional Study · 2026
5Stimulation of Naïve Adipose-Derived Stem Cells with Mesenteric Lymph from Chronic Alcohol-Fed Rats Induces IL-33 Release Associated with Cellular Necrosis2024