Paired clinical description reveals shared neurological manifestations in patients after SARS-CoV-2 infection or vaccination, indicating common anti-ACE2 antibody involvement.
A potential overlap in symptoms between post-acute COVID-19 syndrome and post-COVID-19 vaccination syndrome has been noted. We report a paired description of patients presenting with similar manifestations involving the central (CNS) or peripheral nervous system (PNS) following SARS-CoV-2 infection or vaccination, suggesting that both may have triggered similar immune-mediated neurological disorders in the presence of anti-idiotype antibodies directed against the ACE2 protein.
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Bellucci et al. (2024) studied this question.
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