Preclinical study investigates lipid metabolism and microbiota composition in rat offspring, highlighting potential pathways linking maternal cannabis exposure to neuropathology.
Recent studies have demonstrated that prenatal exposure to the psychoactive ingredient of cannabis that is tetrahydrocannabinol (THC) disrupts fatty acid (FA) signaling pathways in the developing brain, potentially linking to psychopathologic consequences. Our research aims to investigate whether changes in midbrain FA metabolism are linked to modifications in peripheral metabolism of FAs and shifts in microbiota composition.
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Murru et al. (2024) studied this question.
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