Extract and Fixed Oil of Moroccan Lavandula dentata Aerial Parts as Potential Antioxidants

Aromatic and medicinal plants constitute a vast source of bioactive compounds, with remarkablechemical diversity. The aim of the present study is to investigate the antioxidant activity ofextracts and fixed oils of Lavandula dentata L. aerial parts. Dried powdered aerial parts ofLavandula dentata was extracted with methanol by refluxing. Different solvent fractions ofaqueous methanol extract of L. dentata aerial part were prepared by successive extraction inchloroform, ethyl acetate, and n-butanol in order of increasing polarity. Fixed oil of L. dentataaerial parts was obtained by maceration in chloroform at room temperature. Total phenolic andflavonoid contents of the crude methanol extract was determined using standard methods. Theantioxidant activity of the crude methanol extract, fractions, and fixed oil was evaluated usingthe 2,2-diphenyl-1-picryl hydrazyl (DPPH) free radical scavenging assay. Total polyphenolicand flavonoid contents determination revealed that L. dentata crude methanol extract have highcontents of polyphenols (27.43 mg GAE/g), and flavonoids (20.62 mg QE/g). The ethyl acetatefraction of L. dentata exhibited the highest antioxidant activity with IC50 value of 16.41 ± 0.11µg/mL as measured by the DPPH radical scavenging assay. The n-butanol extract alsodemonstrated notable antioxidant activity with IC50 value of 42.32 ± 0.86 µg/mL. The fixed oilextracted from L. dentata aerial parts demonstrated mild antioxidant activity, with IC50 of 414.2mg/mL. The findings from this study have shown that Lavandula dentata aerial parts containsbioactive compounds with antioxidant potentials.