Response to Article “A Study of the Effect of Treatment on the Clinical Profile, Pain, and Disability in Migraine Patients Seen in a Tertiary Hospital” [Letter]

We congratulate Kandasamy et al for successfully conducting research studying the effect of treatment on the clinical profile, pain, and disability in migraine patients seen in a tertiary hospital. 1owever, after reviewing this research carefully, we suggest adding the ethical clearance because the study using humans.While certain observational studies may not subject patients to experimental treatments, they still pose risks such as breaches of confidentiality, the use of invasive outcome measures (like questionnaires or additional tests), increased financial and time burdens from extra visits, and heightened surveillance that could induce anxiety and unnecessary investigations. 2Besides that, the study must be declaring the location of the sampling, so we can know where the cases come from.The type of migraine also needs to be added according to the third edition of the International Classification of Headache Disorders (ICHD-3); migraine is categorized into three primary types: migraine without aura, migraine with aura, and chronic migraine.It is essential to evaluate the clinical features of each type thoroughly to achieve an accurate diagnosis. 3e sincerely thank you for your concern and look forward to continued efforts in migraine research one day.