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August 1, 2024PNAS NexusOpen Access

Development of a novel bacterial production system for recombinant bioactive proteins completely free from endotoxin contamination

Go Kamoshida Daiki Yamaguchi Yuki Kaya Toshiki Yamakado Kenta Yamashita Moe Aoyagi Saaya Nagai Noriteru Yamada Yu Kawagishi Mizuki Sugano Yoshiaki Sakairi Mikako Ueno Norihiko Takemoto Yuji Morita Yukihito Ishizaka Kinnosuke Yahiro

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Abstract

Endotoxins, or lipopolysaccharides (LPS), are potent immunostimulatory molecules of critical concern in bacterial recombinant protein expression systems. The gram-negative bacterium

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Cite This Study

Kamoshida et al. (2024) studied this question.

synapsesocial.com/papers/68e5dfcbb6db643587573ef7 https://doi.org/10.1093/pnasnexus/pgae328

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