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August 1, 2024Open Access

Supplementary Fig. S3 from A Proof-of-Concept Study of Sequential Treatment with the HDAC Inhibitor Vorinostat following BRAF and MEK Inhibitors in BRAFV600-Mutated Melanoma

Alaa Embaby Sanne C.F.A. Huijberts Liqin Wang Rodrigo Leite de Oliveira Hilde Rosing Bastiaan Nuijen Joyce Sanders Ingrid Hofland Charlaine van Steenis Roelof J.C. Kluin Cor Lieftink Christopher G. Smith Christian U. Blank Johannes V. van Thienen John B.A.G. Haanen Neeltje Steeghs Frans L. Opdam Jos H. Beijnen Alwin D. R. Huitema René Bernards Jan H.M. Schellens Sofie Wilgenhof

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Abstract

Supplementary Fig. S3. 4-AOA plasma concentrations over time on days 1 and 14 of the first treatment cycle.

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Embaby et al. (2024) studied this question.

synapsesocial.com/papers/68e5e0e7b6db6435875752bc https://doi.org/10.1158/1078-0432.26422469.v1

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Fig. S3 from A Proof-of-Concept Study of Sequential Treatment with the HDAC Inhibitor Vorinostat following BRAF and MEK Inhibitors in <i>BRAF</i><sup><i>V600</i></sup>-Mutated Melanoma2024
2Supplementary Fig. S2 from A Proof-of-Concept Study of Sequential Treatment with the HDAC Inhibitor Vorinostat following BRAF and MEK Inhibitors in <i>BRAF</i><sup><i>V600</i></sup>-Mutated Melanoma2024
3Supplementary Fig. S2 from A Proof-of-Concept Study of Sequential Treatment with the HDAC Inhibitor Vorinostat following BRAF and MEK Inhibitors in <i>BRAF</i><sup><i>V600</i></sup>-Mutated Melanoma2024
4Supplementary Fig. S4 from A Proof-of-Concept Study of Sequential Treatment with the HDAC Inhibitor Vorinostat following BRAF and MEK Inhibitors in <i>BRAF</i><sup><i>V600</i></sup>-Mutated Melanoma2024
5Supplementary Fig. S4 from A Proof-of-Concept Study of Sequential Treatment with the HDAC Inhibitor Vorinostat following BRAF and MEK Inhibitors in <i>BRAF</i><sup><i>V600</i></sup>-Mutated Melanoma2024