Profile of D-Dimer Levels in Patients Confirmed Positive for COVID-19 at the Indonesian Christian University Hospital

Aims: the research aimed to determine the profile of d-dimer levels in patients confirmed positive for COVID-19 at UKI Hospital from December 2020 to September 2021 Study Design: This type of research is descriptive research with a retrospective cross-sectional research design, namely using secondary data in the form of UKI RS medical records. Place and Duration of Study: The research was carried out in the medical records section of RS UKI from May to October 2021. Methodology: The research samples were all medical records of patients suffering from COVID-19 with an age range of 18 to 45 years and their D-Dimer levels were checked during treatment at UKI Hospital for the period December 2020 to September 2021, totaling 148 samples. This data will be processed and analyzed using the Chi-Square Test. Results: From the results of the study, it was found that there were 129 patients (87.2%) with COVID-19 who had normal D-Dimer levels and 19 patients (12.8%) who had elevated D-Dimer levels. Obtained a p-value of 0.677, which means that there is no statistically significant relationship between clinical symptoms and increased levels of D-Dimer in COVID-19 patients. However, there is a statistically significant relationship between the administration of anticoagulants and an increase in D-Dimer levels in COVID-19 patients with a p-value of 0.015. Conclusion: It can be concluded that there is a significant relationship between anticoagulants and D-Dimer levels in COVID-19 patients with moderate and severe symptoms (in this case administration of anticoagulants can inhibit the increase in D-Dimer), but researchers did not find a significant relationship with mild symptoms.