Postpolypectomy Bleeding Gone Wrong: Primary Colonic Epithelioid Angiosarcoma

Epithelioid angiosarcoma is an aggressive form of angiosarcoma, and primary colonic tumors are extremely rare. We present the case of a 60-year-old man who presented with what initially appeared to be postpolypectomy bleeding. After undergoing repeat endoscopy, he was found to have epithelioid angiosarcoma of the transverse colon, and imaging further confirmed that it was the primary tumor site. Our patient underwent segmental resection of his transverse colon. The patient's initial presentation as postpolypectomy bleeding and his continued cancer-free survival after a relatively limited surgery are unique features not previously seen.