Assessment of Quality of Life in Patients with Chronic Kidney Disease Undergoing Hemodialysis based on Physical, Social, Emotional and Mental Statuses

Aim: To assess the quality of life in patients with Chronic Kidney Disease (CKD) who were undergoing hemodialysis based on their physical, social, emotional and mental statuses. Methods: This was a prospective observational study. Patients of both the genders with an age of above 35 years who were diagnosed with Chronic Kidney Disease (CKD) especially with stage III, IV, V and with a glomerular filtration rate of <30ml/min were included in this study whereas, patients with acute kidney disease were excluded from the study. In this study, SF-36 questionnaire was used for the assessment of quality of life among the patients with ESRD who is undergoing haemodialysis. The score may ranges from 0-100 and the interpretation includes higher the score indicates favorable health state and lower the score indicates more the disability. The patients were interviewed twice, with a time gap of 45 days from the date of first interview and were represented as V0 (Day-1) and V1 (Day-45). Results: A total of 117 subjects were recruited in this study. The mean PCS value at V0 was observed to be 42.9 which was reduced to 40.3 at V1 with a mean difference score of 2.6. The mean MCS value at V0 was observed to be 49.3 which was reduced to 43.3 at V1 with a mean difference score of 6. The PCS scores were observed to be increased among 31.6% study participants whereas it was observed to be decreased among 65%. No change in the aspect of PCS scores were observed among 3.4% study participants. The MCS scores were observed to be increased among 32.5% whereas it was observed to be decreased among 66.7%. No change in the aspect of MCS scores were observed among 0.8% study participants. Conclusion: Based on the mean scores observed, the quality of life was slightly decreased among the study participants who were undergoing hemodialysis because of the changes in PCS & MCS at V0 and V1. Proper patient education must be provided by the clinical pharmacists will help the patient in the better management of CKD and also regarding the health related quality of life.