July 30, 2024Open Access

Targeting tumor-infiltrating CCR8+ regulatory T cells induces antitumor immunity through functional restoration of CD4+ Tconvs and CD8+ T cells in colorectal cancer

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Abstract

Chemokine (C-C motif) receptor 8 (CCR8) is a chemokine receptor selectively expressed on tumor-infiltrating regulatory T cells (Tregs). Strong immunosuppression mediated by CCR8

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Chen et al. (Tue,) studied this question.

synapsesocial.com/papers/68e5e6e9b6db64358757b6ef https://doi.org/https://doi.org/10.1186/s12967-024-05518-8

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