Formulation and Evaluation of Polyherbal Gel for Management of Mouth Ulcer

The main purpose of this gel formulation of Guava leaves, Betel Leaves, Honey and Peppermint oil was to relieve pain and discomfort due to oral ulcers. As we know there are different types of ulcers in the mouth that cause inflammation and pain. The most common oral ulcers are Local trauma & Aphthous Stomatitis. Now many over-the-counter medications are essential to staying in primary healthcare because of the positive response and the most effective treatment with the least amount of side effects. Herbal medicines are still the backbone of almost 75-80%of the world'spopulation, especially in developing countries, in primary healthcare due to better adherence to the human body, cultural acceptance and less side effects. They are found mainly in tropical and subtropical regions of India, the Americas and Africa, where they occur in various countries. The gel contains the main ingredients Guava Leaves Powder, Betel Leaves powder, peppermint oil& Carbopol 934 as a gelling agent & and Propylene glycol as a co-solvent. Another ingredient Honey acts as an antiseptic. The formulated gel was tested for different parameters such as physicochemical parameters (pH, viscosity, Gel strength, etc.). The gel is homogeneous mixture that shows the pH 6.8. Developed herbal oral formulation was stable, safe and effective for treatment of mouth ulcer.